Hyperthyroidism as a Cause of Heart Failure
Keywords:
hyperthyroidism; heart failure; cardiovascular system; thyroid hormoneAbstract
Hyperthyroidism can lead to heart disease because increased thyroid hormone levels produce changes in heart rate, contractility, and relaxation of the heart, which can cause myocardial damage and thus develop ventricular hypertrophy and cardiac dysfunction.
We present the case of a 45-year-old male patient with a history of apparent health who came to the clinic complaining of shortness of breath upon slight exertion, edema in the lower limbs, jugular vein engorgement, and extreme anxiety. He reported a weight loss of 15 kg in 5 months. He was diagnosed with hyperthyroidism as the cause of heart failure. He received treatment with propylthiouracil and propranolol, and the clinical symptoms resolved after 6 months, progressing favorably.
Keywords: hyperthyroidism; heart failure; cardiovascular system; thyroid hormone.
Downloads
References
1. Dzebu AS, González Gorrín M, Gutierrez López A. Hipertiroidismo e insuficiencia cardíaca. CorSalud. 2023 [acceso 20/08/2025];15(3). Disponible en: https://revcorsalud.sld.cu/index.php/cors/article/view/9562023
2. Serna-Trejos Juan Santiago, Lenis-González Juan Pablo. Hipertiroidismo y falla cardíaca una asociación silente. Rev Cuban Med. 2023 [acceso 20/08/2025];62(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S003475232023000200007&lng=es
3. Sadiq AM, Chamba NG. Challenges in the Management of Thyrotoxicosis Associated with Atrial Fibrillation and Heart Failure: Two Case Reports. Clin Med Insights Case Rep. 2021;14. DOI: https://url.org/10.1177/1179547621994573
4. Lee JY, Lee SH, Kim WH. Reversible severe tricuspid regurgitation associated with Graves' disease: A case report. Medicine (Baltimore). 2021;100(51):e28432. DOI: https://doi.org/scielo.php?script=sci_arttext&pid=S185238622010000400003&lng=es.0.1097/md.0000000000028432
5. Mantilla Diego, Echin Mónica Liliana, Perel Cecilia. Hipertiroidismo y sistema cardiovascular: Bases fisiopatológicas y su manifestación clínica. Insuf Card. 2010 [acceso 20/08/2025];5(4):157-77. Disponible en: https://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S185238622010000400003&lng=es.
6. Ahmed AM, Ahmed NH. History of disorders of thyroid dysfunction. East Mediterr Health J. 2005 May;11(3):459-69.
7. Pérez-Stachowski J, Crespo-González E, Aguilar-García J, Romero-Gómez C, García-Alegría J. Varón joven con insuficiencia cardíaca derecha e hipertensión pulmonar. Rev Esp Casos Clin Med Intern. 2016 [acceso 19/08/2025];1:38-40. Disponible en: https://www.reccmi.com/RECCMI/article/view/760
8. Mantilla Diego. Hipertiroidismo y sistema cardiovascular: A propósito de un caso. Insuf Card. 2011 [acceso 18/08/2025];6(3):151-4. Disponible en: https://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S185238622011000300007&lng=es.
9. Diepenbroek SM, de Jonghe A, van Rees C. Heart failure as a serious complication of iodinated contrast-induced hyperthyroidism: case-report. BMC Endocr Disord. 2021;21:207. DOI: https://url.org/10.1186/s12902-021-00870-y
10. Vale C, Neves JS, von Hafe M, Borges-Canha M, Leite-Moreira A. The Role of Thyroid Hormones in Heart Failure. Cardiovasc Drugs Ther. 2019;33(2):179-88. DOI: http://dx.url.org/10.1007/s10557-019-06870-44.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Claudia Fernández Oceguera, Yiliam Blanco Pérez, Caridad Chao Pereira
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The Cuban Journal of Medicine protects the author's patrimonial rights. However, it is licensed under a Creative Commons Licensehttps://creativecommons.org/licenses/by-nc/4.0/deed.es_ES which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided that the primary source of publication is duly cited. The author always retains his moral rights.
You are free to:
- Share - copy and redistribute the material in any medium or format.
- Adapt - remix, transform and build upon the material
- The license cannot revoke these freedoms as long as you follow the terms of the license.
Under the following terms:
- Attribution - You must give proper credit, provide a link to the license, and indicate if changes have been made. You may do so in any reasonable manner, but not in such a way as to suggest that you or your use is supported by the licensor.
- Non-Commercial Purpose- You may not make use of the material for commercial purposes.
- No Additional Restrictions - You may not apply legal terms or technological measures that legally restrict others from making any use permitted by the license.
