Rupture Predictive Factors for Intracranial Aneurysms

Authors

Keywords:

intracranial aneurysms, predictive factors, Logistic regression.

Abstract

Introduction: A ruptured intracranial aneurysm causes a subarachnoid hemorrhage. The disease has high mortality and morbidity. However, not all of them break. Improving the rupture prediction will allow preventive surgical treatment in a group of patients and it will avoid risky surgical intervention in another group of patients. It is necessary to identify predictive factors to improve rupture risk stratification and to optimize treatment of incidental intracranial aneurysms.

Objective: To identify rupture predictive factors for intracranial aneurysms.

Methods: Measurements of the morphological indices or factors were performed in a sample of 152 patients from Sancti Spiritus with ruptured (n = 138) and unruptured (n = 22) saccular intracranial aneurysms and 160 computed tomography angiography images. They were combined using logistic regression analysis with demographic and clinical variables.

Results: The age group with the highest frequency of aneurysm presentation was older than 65. The sample was represented, in its vast majority, by the female sex. Three clinical factors and four statistically significant morphological factors associated with rupture were identified. The non-sphericity index (p = 0.002) and the female sex (p = 0.02) were the most statistically significant.

Conclusions: Seven statistically significant predictors of intracranial aneurysm rupture were detected, the non-sphericity index being the most significant.

 

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Author Biography

Jorge Félix Companioni Rosildo, UCM Sancti.Spiritus

Especialista de primer grado de Neurocirugía(1998), Especialista de segundo grado en Neurocirugía(2011), Máster en Urgencias Médicas (2011), Profesor Auxiliar de Neurocirugía (2011), Doctorando en Neurocigía(2022)

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Published

2023-05-26

How to Cite

1.
Companioni Rosildo JF. Rupture Predictive Factors for Intracranial Aneurysms. Rev Cubana Med [Internet]. 2023 May 26 [cited 2025 Apr. 4];62(2). Available from: https://revmedicina.sld.cu/index.php/med/article/view/3266

Issue

Vol. 62 No. 2 (2023): abril-junio

Section

Original articles

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