Patogenia de la diabetes mellitus no insulinodependiente. Revisión bibliográfica
Abstract
Al igual que la diabetes mellitus insulinodependiente (DMID), los estudios patogénicos de la diabetes mellitus no insulinodependiente (DMNID) han demostrado lo heterogéneo del síndrome. Se ha comprobado que la mayoría de los DMNID son obesos, aunque también los hay no obesos y con una base genética. En los DMNID obesos, se ha descrito sensibililad disminuida del mecanismo glucorreceptor, grados variables de secreción de insulina, lo que incluye la hiperinsulinemia-resistencia insulínica. En los DMNID no obesos, se ha postulado que en el fracaso del glucorreceptor de la célula beta desempeñe algún papel la prostaglandina E. Es planteado también que en la DMNID, el eje entero- insular, glucose-dependent-insulinotropic polypectide (GIP) influye en la insulinosecre- ción. Las consideraciones antes realizadas, evidencian la heterogeneidad de la diabetes y, por ende, lo variable e individual de su tratamiento.Downloads
Downloads
Published
How to Cite
Issue
Section
License
The Cuban Journal of Medicine protects the author's patrimonial rights. However, it is licensed under a Creative Commons Licensehttps://creativecommons.org/licenses/by-nc/4.0/deed.es_ES which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided that the primary source of publication is duly cited. The author always retains his moral rights.
You are free to:
- Share - copy and redistribute the material in any medium or format.
- Adapt - remix, transform and build upon the material
- The license cannot revoke these freedoms as long as you follow the terms of the license.
Under the following terms:
- Attribution - You must give proper credit, provide a link to the license, and indicate if changes have been made. You may do so in any reasonable manner, but not in such a way as to suggest that you or your use is supported by the licensor.
- Non-Commercial Purpose- You may not make use of the material for commercial purposes.
- No Additional Restrictions - You may not apply legal terms or technological measures that legally restrict others from making any use permitted by the license.
