Acción deí atenolol y la tiamenidina en las arritmias inducidas por cloroformo en ratones

Authors

  • Alberto González-Gómez ECIMED
  • Alicia Zapata Martínez ECIMED
  • David García Barreto ECIMED
  • Miguel García Rodríguez ECIMED

Abstract

Se utilizó una sencilla técnica de screeningpara determinar la posible acción antiarrítmica del atenolol y la tiamenidina en ratones albinos de uno y otros sexos. Las dosis efectivas medias (DE50) fueron de 0,8399 ± 0,0015 mg/kg y 3 ± 1,2 mg/kg para el atenolol y la tiamenidina, respectivamente. Ambas drogas previnieron la fibrilación ventricular inducida por el cloroformo a través de mecanismos diferentes.

Downloads

Download data is not yet available.

Downloads

Published

2020-07-30

How to Cite

1.
González-Gómez A, Zapata Martínez A, García Barreto D, García Rodríguez M. Acción deí atenolol y la tiamenidina en las arritmias inducidas por cloroformo en ratones. Rev Cubana Med [Internet]. 2020 Jul. 30 [cited 2025 Mar. 14];19(5). Available from: https://revmedicina.sld.cu/index.php/med/article/view/1540

Issue

Vol. 19 No. 5 (1980)

Section

Original articles

License

The Cuban Journal of Medicine protects the author's patrimonial rights. However, it is licensed under a Creative Commons Licensehttps://creativecommons.org/licenses/by-nc/4.0/deed.es_ES which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided that the primary source of publication is duly cited. The author always retains his moral rights.

 

You are free to:

- Share - copy and redistribute the material in any medium or format.

- Adapt - remix, transform and build upon the material

- The license cannot revoke these freedoms as long as you follow the terms of the license.

Under the following terms:

- Attribution - You must give proper credit, provide a link to the license, and indicate if changes have been made. You may do so in any reasonable manner, but not in such a way as to suggest that you or your use is supported by the licensor.

- Non-Commercial Purpose- You may not make use of the material for commercial purposes.

- No Additional Restrictions - You may not apply legal terms or technological measures that legally restrict others from making any use permitted by the license.