Diabetic Gastroparesis in Patients with More Than 10 Years of Disease Duration
Keywords:
gastroparesis; diabetes mellitus; gastric emptying.Abstract
Introduction: Diabetic gastroparesis has long been underdiagnosed.
Objective: To characterize patients with diabetic gastroparesis of more than 10 years' duration.
Methods: A descriptive and retrospective study was conducted on 61 patients with diabetic gastroparesis. They were divided into two groups according to type of diabetes. The variables studied were age, sex, type of diabetes, duration of disease, smoking status, hypertension, nutritional status, fasting glucose, HbA1c, cholesterol, triglycerides, symptoms, severity of delayed gastric emptying, and chronic complications. For statistical analysis, the mean and standard deviation (SD) were used for quantitative variables; frequency (%) for qualitative variables. The chi-square test or Fisher's exact test was used to associate qualitative variables. The significance level was set at p < 0.05.
Results: It was found that 54.0% vs. 64.0% of patients with type 1 diabetes (T1D) had poor glycemic control (PGC) in type 1 (T1D) and type 2 (T2D), respectively. The predominant age group was 40-49 years in T1D and over 60 years in T2D, and the majority were female. The duration of diabetes was less than 20 years in 70% of T1D patients and between 10-15 years in T2D patients (p = 0.001). 65.0% of T1D patients were of normal weight and 56.1% of T2D patients were obese (p < 0.001). Smokers (57.4%) and hypertensive patients (70.0% vs. 90.2%; p < 0.001) were more prevalent. The worst glycemic control was observed in T2D patients (59.0% vs. 64.0% in T2D). 45.0%, respectively, HbA1c > 8% (60.7%), cholesterol (45.0% vs. 53.7%), and triglycerides (15.0% vs. 48.8%; p < 0.001). The predominant symptoms were early satiety and mild gastric emptying delay, cardiovascular disease (20.0% vs. 80.5%; p < 0.001), and neurogenic bladder (20.0% vs. 61.0%; p < 0.016).
Conclusions: Diabetic gastroparesis was associated with disease duration, nutritional status, hypertension, hypertriglyceridemia, cardiovascular disease, and neurogenic bladder.
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Copyright (c) 2026 Noraika Domínguez Pacheco, José Efraín Gómez Manzanares, Sergio Enrique Zayas Puig, Marisela Nuez Vilar, Idania María Reyes Martínez
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