Chronic Tophaceous Gout with a Tumor-Like Appearance and Reconstruction of Osteoarticular Damage by Three-Dimensional Computed Tomography

Authors

  • José Antonio Martínez Quesada Centro de Investigaciones Médico Quirúrgicas https://orcid.org/0000-0001-7876-5044
  • Gil Reyes Guibert Centro de Investigaciones Médico Quirúrgicas
  • Denis Carrillo Lovet
  • Leyla Otaño Albuerne
  • Marlene Guibert Toledano
  • Gil Alberto Reyes LLerena Centro de Investigaciones Médico Quirúrgicas. Cols. Centro Nacional de Reumatología, Policlínico Docente Cristóbal Labra. La Lisa, Habana Cuba.

Keywords:

tophaceous gout; computed tomography; three-dimensional.

Abstract

Introduction: Chronic tophaceous gout with a tumor-like appearance represents the final and most disabling stage of gout, in which early diagnosis and treatment are crucial to prevent devastating complications.

Objective: To describe the evolution of a clinical case of complicated gout with systemic involvement in a patient who is not adherent to treatment.

Case report: We present a complex clinical case of a 57-year-old black male patient with moderate hypertension. He presented with podagra attacks in 2003 and was diagnosed with gouty arthritis based on sustained hyperuricemia and recurrent acute inflammatory joint attacks. He has received irregular treatment for years and has been hospitalized several times for severe acute gout attacks, systemic renal and cardiovascular complications, progressing to severe chronic polyarticular tophaceous arthritis.

Conclusions: A clinical, metabolic, histochemical, and reconstructive tomographic imaging diagnosis of uncontrolled chronic pathological osteoarticular damage was performed. We also present a concise epidemiological, etiopathogenic, clinical, and therapeutic update on this important global health problem.

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Author Biographies

José Antonio Martínez Quesada, Centro de Investigaciones Médico Quirúrgicas

Especialista de 1er grado en Medicina General Integral, 2do grado en Medicina Interna, Profesor Auxiliar y MsC en Urgencias Médicas. CIMEQ. Cuba. Orcid.*000-0001-5114-5144

Gil Reyes Guibert, Centro de Investigaciones Médico Quirúrgicas

Especialista en Medicina General Integral, Residente 2do año en Reumatología. Centro Nacional de Reumatología. Cuba. Orcid-**0009-0000-0049-3472

Denis Carrillo Lovet

Especialista de 1er grado en Medicina Interna. CIMEQ. Cuba. Orcid ***0000-0003-0987-185X

Gil Alberto Reyes LLerena, Centro de Investigaciones Médico Quirúrgicas. Cols. Centro Nacional de Reumatología, Policlínico Docente Cristóbal Labra. La Lisa, Habana Cuba.

Dr.C, Especialista de 1er grado en Medicina Interna, 2do grado en Reumatología, Profesor Titular, Investigador Titular, MsC en Infectología,  Académico Titular de la Academia de Ciencias de Cuba. Orcid******.0000-0001-7749-5652

Published

2026-02-15

How to Cite

1.
Martínez Quesada JA, Reyes Guibert G, Carrillo Lovet D, Otaño Albuerne L, Guibert Toledano M, Reyes LLerena GA. Chronic Tophaceous Gout with a Tumor-Like Appearance and Reconstruction of Osteoarticular Damage by Three-Dimensional Computed Tomography. Rev Cubana Med [Internet]. 2026 Feb. 15 [cited 2026 Mar. 1];65. Available from: https://revmedicina.sld.cu/index.php/med/article/view/4966

Issue

Section

Case Reports