Paraneoplastic Pemphigus Initial Manifestation of Renal Tumor

Authors

  • Elisa Ortúzar Menesia Hospital Hermanos Ameijeiras
  • José Ramón Alduenda Ceja Hospital Hermanos Ameijeiras
  • Kirenia Rodríguez Pérez Hospital Clinico Quirurgico Hermanos Ameijeiras https://orcid.org/0000-0002-6830-548X

Keywords:

paraneoplastic pemphigus, kidney tumor, oral stomatitis.

Abstract

Introducción: Paraneoplastic pemphigus is an autoimmune blistering disease associated with an occult or previously diagnosed neoplasia, with well-defined clinical, histological and immunological manifestations.

Objective: To present paraneoplastic pemphigus associated with kidney tumor.

Case report: A 47-year-old male patient was reported, with a history of bronchial asthma since childhood, high blood pressure for three years, in addition to having cataract and gastroesophageal reflux due to hiatal hernia, motivating his admission due to erosive lesions of his oral mucosa, painful with hemorrhagic crusts and saliva affecting the cheeks, tongue, gums, as well as lesions in the conjunctival and nasal mucosa. Histopathology revealed acantholysis and necrotic keratinocytes, respectively. The presence of a kidney tumor confirmed the diagnosis. Embolization of the kidney tumor was performed together with high doses of corticosteroids for the cutaneous-mucosal lesions, with good response to said treatment, although the presence of paraneoplastic pemphigus associated with a kidney tumor is rare and should be taken into account among the differential diagnoses of periorificial erosive dermatoses.

Conclusions: It is essential to recognize the importance of the correlation of clinicopathological and immunological findings in paraneoplastic pemphigus, as well as the possibility of presentations that require prompt confirmation and immunopathological evaluation of an occult neoplasia.

Downloads

Author Biographies

Elisa Ortúzar Menesia, Hospital Hermanos Ameijeiras

. MsC. Especialista de 1er Grado en Dermatología. Profesora Instructora. Hospital Hermanos Ameijeiras. La Habana, Cuba. Correo electrónico: elisaortuzar2015@gmail.com ORCID: https: //orcid.org/ 0000-0003-1904-8314.

José Ramón Alduenda Ceja, Hospital Hermanos Ameijeiras

. Especialista de 1er Grado en Dermatología. Hospital Hermanos Ameijeiras. La Habana, Cuba. ORCID: https: //orcid.org/ 0000-0003-2362-6703.

Kirenia Rodríguez Pérez, Hospital Clinico Quirurgico Hermanos Ameijeiras

Especialista de 1er grado de Dermatologia, en Hopsital Clinico Quirurgico: Hermanos Ameijeiras.

Downloads

Published

2024-06-04

How to Cite

1.
Ortúzar Menesia E, Alduenda Ceja JR, Rodríguez Pérez K. Paraneoplastic Pemphigus Initial Manifestation of Renal Tumor. Rev Cubana Med [Internet]. 2024 Jun. 4 [cited 2025 Jul. 26];63. Available from: https://revmedicina.sld.cu/index.php/med/article/view/3304

Issue

Vol. 63 (2024): publicación continua

Section

Case Reports

License

The Cuban Journal of Medicine protects the author's patrimonial rights. However, it is licensed under a Creative Commons Licensehttps://creativecommons.org/licenses/by-nc/4.0/deed.es_ES which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided that the primary source of publication is duly cited. The author always retains his moral rights.

 

You are free to:

- Share - copy and redistribute the material in any medium or format.

- Adapt - remix, transform and build upon the material

- The license cannot revoke these freedoms as long as you follow the terms of the license.

Under the following terms:

- Attribution - You must give proper credit, provide a link to the license, and indicate if changes have been made. You may do so in any reasonable manner, but not in such a way as to suggest that you or your use is supported by the licensor.

- Non-Commercial Purpose- You may not make use of the material for commercial purposes.

- No Additional Restrictions - You may not apply legal terms or technological measures that legally restrict others from making any use permitted by the license.