La preparación de radiofármacos marcados con radionúclidos de iodo. II. Preparación de rosa de bengala marcada con 131I

Authors

  • Natalia Rovnij ECIMED
  • Francisco Zayas Crespo ECIMED
  • Leo Kronrad ECIMED
  • Pavel Jradilek ECIMED

Abstract

Se estudia la preparación del radiofármaco rosa de bengala-'31!, utilizando Nal3ll de baja actividad específica y un método de mareaje a partir de un KIT. Se investiga la influencia de los componentes de la reacción de intercambio isotópico en el desarrollo de la misma. Se llega a nuevas conclusiones acerca del mecanismo de la reacción de intercambio, desconocidas hasta ahora a partir de los resultados obtenidos. Se informa que la biodistribución en ratas y el estudio de flujo hepático realizado en conejos indican que el radiofármaco cumple los parámetros requeridos para su utilización en humanos.

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Published

2020-12-18

How to Cite

1.
Rovnij N, Zayas Crespo F, Kronrad L, Jradilek P. La preparación de radiofármacos marcados con radionúclidos de iodo. II. Preparación de rosa de bengala marcada con 131I. Rev Cubana Med [Internet]. 2020 Dec. 18 [cited 2025 Feb. 7];24(9). Available from: https://revmedicina.sld.cu/index.php/med/article/view/2230

Issue

Vol. 24 No. 9 (1985)

Section

Original articles

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